Yoko Nakano, PhD
Associate Research Scientist
Education
MS and PhD - Tokushima University
Postdoctoral Fellow - International Medical Center of Japan
Postdoctoral Fellow - University of Iowa
Mentor
Botond Bánfi
Affiliations
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Department of Anatomy & Cell Biology
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Iowa Inflammation Program
Research Interests
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Identification and functional analysis of deafness gene
Recent Publications
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Nakano Y, Wiechert S, Fritzsch B, Bánfi B. Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Oct 21;3(12):e202000841. doi: 10.26508/lsa.202000841. PMID: 33087486.
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Nakano Y, Wiechert S, Bánfi B. Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8. doi: 10.1016/j.celrep.2019.03.072. PMID: 30995482; PMCID: PMC6556397.
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Nakano Y, Nauseef WM. Spectroscopy of NOX Protein Family Members. Methods Mol Biol. 2019;1982:113-120. doi: 10.1007/978-1-4939-9424-3_7. PMID: 31172469.
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Tona R, Chen W, Nakano Y, Reyes LD, Petralia RS, Wang YX, Starost MF, Wafa TT, Morell RJ, Cravedi KD, du Hoffmann J, Miyoshi T, Munasinghe JP, Fitzgerald TS, Chudasama Y, Omori K, Pierpaoli C, Banfi B, Dong L, Belyantseva IA, Friedman TB. The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy. Hum Mol Genet. 2019 May 1;28(9):1530-1547. doi: 10.1093/hmg/ddy445. PMID: 30602030; PMCID: PMC6466106.
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Nakano Y, Kelly MC, Rehman AU, Boger ET, Morell RJ, Kelley MW, Friedman TB, Bánfi B. Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness. Cell. 2018 Jul 26;174(3):536-548.e21. doi: 10.1016/j.cell.2018.06.004. Epub 2018 Jun 28. PMID: 29961578; PMCID: PMC6370011.